T cells engineered with chimeric antigen receptors (CARs) have emerged as a potent new class of therapeutics for cancer, based on their remarkable potency in blood cancers.Since the first clinical PCB reports of their efficacy emerged 7 years ago, investigators have focused on the mechanisms and properties that make CARs effective or toxic, and the
Studies have shown that the effects of early-life stress and trauma can be enduring, with long-term negative effects on health.Epigenetics, including DNA methylation, have been implicated as a potential mechanism for these effects.Brain-derived neurotropic factor (BDNF) is a neurotransmitter involved in learning and memory, and altered BDNF promote
Abstract Background Infants in utero during the terrorist attacks of September 11, 2001 may have been negatively affected by maternal stress.Studies to date have produced contradictory results.Methods Data for this retrospective cohort study were obtained from the Department of Defense Birth and Infant Health Registry and included up to 164,743 inf
Shaheen C Kavoussi, James E Kempton, John J Huang Yale University Department of Ophthalmology and Visual Science, New Haven, CT, USA Abstract: An otherwise healthy 24-year-old man presented with a painless decrease of vision in the left eye for 2 days.Best-corrected visual acuity was 20/20 in the right eye and 20/80 in the left eye.Anterior exam wa
This research is based on this assumption that the ways people are represented in TV are different with the ways they are represented on social media such as Instagram because the nature of social media is different with the nature of mass media.Thus the users of social media when using these media to represent their daily lives, actively use these